Background: IL1RA is a member of the Interleukin 1 cytokine family. This protein inhibits the activities of Interleukin 1, alpha (IL1A) and Interleukin 1, beta (IL1B), and modulates a variety of Interleukin 1 related immune and inflammatory responses. This gene and five other closely related cytokine genes form a gene cluster spanning approximately 400 kb on chromosome 2. A polymorphism of this gene is reported to be associated with increased risk of osteoporotic fractures and gastric cancer. Four alternatively spliced transcript variants encoding distinct isoforms have been reported.
Specification : 100ul
Host species/Isotype : Rabbit/IgG
Cross reaction : Human, Mouse, Rat
Immunogen : KLH conjugated synthetic peptide derived from human IL-1RA.
Storage instructions: Store at -20℃ for one year. Avoid repeated freeze/thaw cycles.
Concentration : 1mg/ml
Purity : affinity purified by Protein A
Clonality : Polyclonal
Molecular weight: 17KDa
Tested applications:
WB=1:500-2000
ELISA=1:500-1000
IHC-P=1:100-500
IHC-F=1:100-500
IF=1:100-500
產(chǎn)品貨號:GS48926