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商品編號


CM10004806



品牌


IBL



公司


IBL,inc



公司分類(lèi)


Antibodies


商品信息

Quantity / Tests
100 ?g
Species / Antigen
Human p53 / N-terminal amino acids 16-25
Host
Mouse
Subclass / Clone
IgG2a / BP53-12
Type
Monoclonal
Purification
N/A
Label
N/A
Regulatory Status:
For research use only


Details for:


?
p53 Monoclonal Antibody (Clone BP53-12)

Cellular p53, often called the 'guardian of the genome,' is a transcription factor that is activated in response to cellular stress (DNA damage, hypoxia, heat shock, etc.) and acts to prevent further proliferation of the stressed cell by induction of cell cycle arrest or apoptotic mediators. Nearly 50% of human tumors have mutated or non-functional p53. This antibody is suitable for a variety of techniques to distinguish between p53 positive and p53 negative tumors.
For concrete data please consult the Instruction for Use in the download box on the right side.