Adipogen/CD40L [CD154] (human)-muCD8 Fusion Protein (preservative free)/ANC-505-820/25 ?g
其他試劑盒
商品編號
ANC-505-820
品牌
Adipogen
公司
Adipogen
公司分類(lèi)
Immunology
Size
25 ?g
商品信息
More Information
Product Details
Product Type
Protein
Properties
Source/Host
CHO cells
Application
Flow Cytometry
ELISA
Western Blot
Label/Conjugates
Preservative Free
Formulation
50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl
Other Product Data
Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.
Declaration
Manufactured by Ancell Corporation.
Shipping and Handling
Shipping
BLUE ICE
Short Term Storage
+4°C
Long Term Storage
+4°C
Handling Advice
Avoid freeze/thaw cycles.
Use/St
ABI
lity
Stable for at least 6 months after receipt when stored at +4°C.
Documents
MSD
S
No
Product Specification Sheet
Datasheet
Download PDF
Human CD154 (CD40 ligand) is a member of the TNF family and is expressed on the surface of activated T cells. It can undergo proteolytic cleavage into a 19kDa immunologically active soluble form. Interaction of CD154 and CD40 is essential for isotype switching in B cells. Known genetic defects that alter this interaction lead to impaired immune system function. Increased levels of CD154 has been associated with autoimmune disorders including SLE, CLL and eosinophilic fasciitis. CD154 has been reported to be expressed on vascular endothelial cells, smooth muscle cells, macrophages and activated platelets indicating a role for the CD40-CD154 immunoregulatory signaling in artherosclerosis and cardiovascular disorders.
產(chǎn)品貨號:4189.6