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Sigma-Aldrich/Fmoc-Asp(O-2-PhiPr)-OH/8520860001/8520860001

多肽
Sigma-Aldrich/Fmoc-Asp(O-2-PhiPr)-OH/8520860001/8520860001


商品編號


8520860001



品牌


西格瑪奧德里奇(Sigma-Aldrich)



公司


Merck & Co., Inc.



公司分類(lèi)


Chemistry



Size

8520860001

商品信息

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Synonym:

N-α-Fmoc-L-aspartic acid β-2-phenylisopropyl ester

CAS Number
200336-86-3



Linear Formula
C??H??NO?



Molecular Weight
473.52?g/mol

Properties:

Related Categories

Amino Acids & Derivatives, Aspartic Acid, Chemical
BIOLOG
y, Chemical Synthesis, Peptide Chemistry
Description:
Background information

Quasi-orthogonally-protected Asp derivative.
The 2-PhiPr group can be removed selectively in the presence of tBu-based protecting groups by treatment with 1% TFA in DCM [1], making this derivative an extremely useful tool for the preparation of cyclic peptides by Fmoc SPPS [2] or for library synthesis. For the on-resin synthesis of side-chain to side-chain lactam bridged peptides, the combination of Lys(Mtt) and Asp(O-2-PhiPr) is particularly advantageous since both side-chains can be simultaneously unmasked in a single step.
This derivative has also been used in solution to prepare bicyclic helix initiating peptides [3].
The product number for this product was previously 04-12-1200
.
To obtain a certificate of analysis (CoA) of a lot that begins with the letter "A", please select the option in the right hand menu "Request a COA for Lot#s starting with A".
Safety:

HS Code?

2924 29 70



Storage class?

10 - 13 Other liquids and solids



WGK?

WGK 2 water endangering

上一篇 Sigma-Aldrich/Fmoc-Asp-O-2PhiPr/8523350001/8523350001  下一篇 Sigma-Aldrich/Fmoc-Asp(EDANS)-OH/8521188500/8521188500

產(chǎn)品貨號:1759.2

1759.2 ¥
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