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商品編號


AG-40A-0127-C010



品牌


Adipogen



公司


Adipogen



公司分類(lèi)


Proteins



Size

10 ?g


商品信息


More Information



Product Details



Synonyms

Fat Mass and Obesity-associated Protein; FATSO



Product Type

Protein



Properties



Source/Host

E. coli



Sequence

Mouse FTO (aa 2-502) is fused at the N-terminus to a His-tag.



Crossreactivity

Mouse



MW

~55kDa (SDS-PAGE)



Purity

≥90% (SDS-PAGE)



Purity Detail

Purified using Ni-NTA column and FPLC.



Endotoxin Content

<1eu mu;g="" purified="" protein="" (lal="" test;="" lonza).="">1eu>



Concentration

~0.5mg/ml



Formulation

Liquid. 0.2μm-filtered solution in 55mM TRIS-Cl, pH 8.2, containing 150mM NaCl.



Other Product Data

UniProt link Q8BGW1: FTO (mouse)



Shipping and Handling



Shipping

BLUE ICE



Short Term Storage

+4°C



Long Term Storage

-20°C



Handling Advice

After opening, prepare aliquots and store at -20°C.
Avoid freeze/thaw cycles.
For maximum product recovery after thawing, centrifuge the vial before opening the cap.



Use/St
ABI
lity

Working aliquots are stable for up to 3 months when stored at -20°C.



Documents



MSD
S


Download PDF



Product Specification Sheet



Datasheet


Download PDF





FTO (Fat mass-and obesity-associated gene) is the respons
IBL
e gene for mouse ‘fused toes’ mutation. An association between FTO genotype and type 2 diabetes has been confirmed. The presence of the FTO rs9939609 A-allele was found to be positively correlated with other symptoms of the metabolic syndrome, including higher fasting insulin, glucose, triglycerides, and lower HDL-cholesterol.