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商品編號


YIF-LF-P0278



品牌


Adipogen



公司


Adipogen



公司分類(lèi)


Proteins



Size

10 ?g

商品信息


More Information



Product Details



Synonyms

CSF; CSF2; GMCSF; GM-CSF; Molgramostin; Sargramostim; Colony-stimulating Factor; Granulocyte-macrophage Colony-stimulating Factor



Product Type

Protein



Properties



Source/Host

E. coli



Crossreactivity

Human



BIOLOG
ical Activity

The ED50 for this effect is typically 10-40 pg/mL. Measured in a cell proliferation assay using the human growth factor-dependent cell line, TF-1.



Purity

≥95% (SDS-PAGE)



Concentration

0.5 mg/ml



Formulation

Liquid in PBS, 10% glycerol.



Other Product Data

Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.



Declaration

Manufactured by AbFrontier



Shipping and Handling



Shipping

DRY ICE



Short Term Storage

-20°C



Long Term Storage

-80°C



Handling Advice

Avoid freeze/thaw cycles.



Documents



MSD
S

No



Product Specification Sheet



Datasheet


Download PDF





Human GM-CSF is a 24 kDa glycoprotein produced by a variety of cell types, including T and B lymphocytes, macrophages, keratinocytes, eosinophils, neutrophils, and endothelial cells in response to cytokine or inflammatory stimuli. GM-CSF was initially identified on the basis of its capacity to stimulate the clonal proliferation of myeloid precursors in vitro. GM-CSF promotes a Th1 biased immune response, allergic inflammation, and the development of autoimmunity. GM-CSF are particularly effective as antitumor vaccines. GM-CSF regulates multiple
BIOLOG
ical activities through activation of the GM-CSF receptor (GMCSFR), a member of the type I cytokine receptor group comprising a and b subunits.


Product References
1) Conti L and Gessani S., (2008) Immuno
BIOLOG
y 213:859-870. (General)
2) Waller EK., (2007) Oncologist 12:22-6. (General)