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商品編號


AG-40A-0037-C050



品牌


Adipogen



公司


Adipogen



公司分類(lèi)


Proteins



Size

50 ?g


商品信息


More Information



Product Details



Synonyms

Glutathione Peroxidase 3; Plasma Glutathione Peroxidase; Extracellular Glutathione Peroxidase; GPx-3; GSHPx-3; GPx-P; GSHPx-P



Product Type

Protein



Properties



Source/Host

HEK 293 cells



Sequence

Human GPX3 (aa 21-226) is fused at the N-terminus to a FLAG
?
-tag.



Crossreactivity

Human



MW

~30kDa (SDS-PAGE)



Purity

≥90% (SDS-PAGE)



Endotoxin Content

<0.1eu mu;g="" purified="" protein="" (lal="" test;="" lonza).="">0.1eu>



Concentration

0.5mg/ml



Formulation

Liquid. 0.2μm-filtered solution in PBS, pH7.2.



Other Product Data


UniProt link P22352: Glutathione peroxidase 3 (human) [Precursor]

FLAG is a registered trademark of
Sigma-Aldrich
Co.




Shipping and Handling



Shipping

BLUE ICE



Short Term Storage

+4°C



Long Term Storage

-20°C



Handling Advice

After opening, prepare aliquots and store at -20°C.
Avoid freeze/thaw cycles.



Use/St
ABI
lity

Working aliquots are stable for up to 3 months when stored at -20°C.



Documents



MSD
S


Download PDF



Product Specification Sheet



Datasheet


Download PDF





Glutathione peroxidase 3 (GPX3) is a selenium-dependent extracellular enzyme, protecting cells and enzymes from oxidative damage by catalyzing the reduction of hydrogen peroxide, lipid peroxides and organic hydroperoxides. GPX3 is involved in inflammatory bowel disease, in asthma and in diabetes. The activity of GPX3 is significantly reduced in the plasma and tissue of cancer patients. Recently, GPX3 was suggested to serve as a molecular
Marker
for the diagnosis of clear cell type ovarian adenocarcinoma.