欧美自拍另类欧美宗合图片区,国产视频一区二区三区四区,日本一区二区三区四区视频,婬片一区AAA毛片一区二区

商品編號


CHI-AG-40A-0159-C050



品牌


Adipogen



公司


Adipogen



公司分類(lèi)


Proteins



Size

50 ?g

商品信息


More Information



Product Details



Synonyms

Glutathione Peroxidase 4; Phospholipid Hydroperoxide Glutathione Peroxidase, Mitochondrial; GPx-4; GSHPx-4; PHGPx



Product Type

Protein



Properties



Source/Host

E. coli



Sequence

Human GPX4 (aa 1-197) is fused at the C-terminus to a His-tag.



Crossreactivity

Human



MW

~23kDa (SDS-PAGE)



Purity

≥90% (SDS-PAGE)



Endotoxin Content

<0.1eu mu;g="" purified="" protein="" (lal="" test;="" lonza).="">0.1eu>



Reconstitution

10?g vial: Reconstitute with 100 ?l sterile water to a concentration of 0.1mg/ml.
50?g vial: Reconstitute with 50 ?l sterile water to a concentration of 1mg/ml.
Add 1X PBS to the desired protein concentration.



Formulation

Lyophilized from 0.2μm-filtered solution in 1X PBS.



Other Product Data

NCBI link AAH11836.1:
GPX4 (human)




Shipping and Handling



Shipping

BLUE ICE



Short Term Storage

+4°C



Long Term Storage

-20°C



Handling Advice

Avoid freeze/thaw cycles.



Use/St
ABI
lity

Stable for at least 1 year after receipt when stored at -20°C.
Working aliquots are stable for up to 3 months when stored at -20°C.



Documents



MSD
S

No



Product Specification Sheet



Datasheet


Download PDF





Glutathione peroxidase 4, also known as GPX4, is an enzyme that in humans is encoded by the GPX4 gene. GPX4 is a phospholipid hydroperoxidase that protects cells against membrane lipid peroxidation. GPX4 catalyzes the reduction of hydrogen peroxide, organic hydroperoxides and lipid peroxides at the expense of reduced glutathione and functions in the protection of cells against oxidative stress. The oxidized form of glutathione (glutathione disulfide), which is generated during the reduction of hydroperoxides by GPX4, is recycled by glutathione reductase and NADPH/H+. GPX4 differs from the other GPX family members in terms of its monomeric structure, a less restricted dependence on glutathione as reducing substrate, and the
ABI
lity to reduce lipid-hydroperoxides inside
BIOLOG
ical membranes.