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商品編號


CHI-AG-40A-0169-C010



品牌


Adipogen



公司


Adipogen



公司分類(lèi)


Proteins



Size

10 ?g

商品信息


More Information



Product Details



Synonyms

HEL-S-75p; Glutathione Peroxidase 5; GSHPx-5; Epididymal Secretory Glutathione Peroxidase; EGLP



Product Type

Protein



Properties



Source/Host

HEK 293 cells



Sequence

The extracellular domain of human GPX5 (aa 24-221) is fused at the C-terminus to a FLAG
?
-tag.



Crossreactivity

Human



MW

~25kDa (SDS-PAGE)



Purity

≥90% (SDS-PAGE)



Endotoxin Content

<0.06eu mu;g="" purified="" protein="" (lal="" test;="" lonza).="">0.06eu>



Reconstitution

10?g vial: Reconstitute with 100 ?l sterile water to a concentration of 0.1mg/ml.
50?g vial: Reconstitute with 50 ?l sterile water to a concentration of 1mg/ml.
Add 1X PBS to the desired protein concentration.



Formulation

Lyophilized from 0.2μm-filtered solution in 1X PBS.



Other Product Data

NCBI link NP_001500.1:
GPX5 (human)




Shipping and Handling



Shipping

BLUE ICE



Short Term Storage

+4°C



Long Term Storage

-20°C



Handling Advice

Avoid freeze/thaw cycles.



Use/St
ABI
lity

Stable for at least 1 year after receipt when stored at -20°C.
Working aliquots are stable for up to 3 months when stored at -20°C.



Documents



MSD
S

No



Product Specification Sheet



Datasheet


Download PDF





Glutathione peroxidase 5 (GPX5), also known as epididymal secretory glutathione peroxidase is an enzyme that in humans is encoded by the GPX5 gene. GPX5 belongs to the glutathione peroxidase family. It is specifically expressed in the epididymis in the mammalian male reproductive tract, and is androgen-regulated. Unlike mRNAs for other characterized glutathione peroxidases, this mRNA does not contain a selenocysteine (UGA) codon. Thus, the encoded protein is selenium-independent, and has been proposed to play a role in protecting the membranes of spermatozoa from the damaging effects of lipid peroxidation and/or preventing premature acrosome reaction. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.