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商品編號


AG-40T-0018-C020



品牌


Adipogen



公司


Adipogen



公司分類(lèi)


Proteins



Size

20 ?g


商品信息


More Information



Product Details



Synonyms

Histone Acetyltransferase PCAF; Histone Acetyltransferase KAT2B; Lysine Acetyltransferase 2B; P/CAF; P300/CBP-associated Factor



Product Type

Protein



Properties



Source/Host

Sf21 cells



Sequence

Mouse PCAF is fused to a His-tag.



Crossreactivity

Mouse



BIOLOG
ical Activity

~100-200ng are required for standard HAT assay.



Purity

≥95% (SDS-PAGE)



Concentration

Lot dependent (0.2-0.5mg/ml)



Formulation

Liquid. In 50mM TRIS-HCl, pH 7.5, containing 100mM sodium chloride, 50mM imidazole, 0.2% NP-40 and 10% glycerol.



Other Product Data

UniProt ID Q9JHD1: PCAF (mouse)



Shipping and Handling



Shipping

DRY ICE



Short Term Storage

-20°C



Long Term Storage

-80°C



Handling Advice

After opening, prepare aliquots and store at -80°C.
Avoid freeze/thaw cycles.



Use/St
ABI
lity

Stable for at least 6 months after receipt when stored at -80°C.



Documents



MSD
S


Download PDF



Product Specification Sheet



Datasheet


Download PDF





PCAF functions as a histone acetyltransferase (HAT) to promote transcriptional activation. It has significant histone acetyltransferase activity with core histones H3 and H4, and also with nucleosome core particles.


Product References

Functional relevance of novel p300-mediated lysine 314 and 315 acetylation of RelA/p65: C. Buerki, et al.; Nucleic Acids Res.
36,
1665 (2008)