Adipogen/Peroxiredoxin 3 (human) (rec.)/YIF-LF-P0023/0.25 mg
重組蛋白
商品編號
YIF-LF-P0023
品牌
Adipogen
公司
Adipogen
公司分類(lèi)
Proteins
Size
0.25 mg
商品信息
More Information
Product Details
Synonyms
AOP1; AOP-1; PRDX3; HBC189; Prx-III; EC=1.11.1.15; Peroxiredoxin-3; Peroxiredoxin III; Protein MER5 Homolog; Antioxidant Protein 1; Thioredoxin-dependent Peroxide Reductase, Mitochondrial
Product Type
Protein
Properties
Source/Host
E. coli
Crossreactivity
Human
BIOLOG
ical Activity
1.2U/mg (One unit will cause the oxidation of 1.0 μmole of NADPH at 25°C at pH7.5)
Purity
≥95% (SDS-PAGE)
Concentration
1 mg/ml
Formulation
Liquid in 20mM HEPES, pH 7.0, 10% Glycerol.
Other Product Data
Click here for Original Manufacturer Product Datasheet
Our product description may differ slightly from the original manufacturers product datasheet.
Declaration
Manufactured by AbFrontier
Shipping and Handling
Shipping
DRY ICE
Short Term Storage
-20°C
Long Term Storage
-80°C
Handling Advice
Avoid freeze/thaw cycles.
Documents
MSD
S
No
Product Specification Sheet
Datasheet
Download PDF
Peroxiredoxin (Prx) is a growing peroxidase family, whose mammalian members have been known to connect with cell proliferation, differentiation, and apoptosis. Many isoforms (about 50 proteins), collected in accordance to the amino acid sequence homology, particularly amino-terminal region containing active site cysteine residue, and the thiol-specific antioxidant activity, distribute throughout all the kingdoms. Among them, mammalian Prx consists of 6 different members grouped into typical 2-Cys, atypical 2-Cys Prx, and 1-Cys Prx. Except Prx 6 belonging to 1-Cys Prx subgroup, the other five 2-Cys Prx isotypes have the thioredoxin-dependent peroxidase (TPx) activity utilizing thioredoxin, thioredoxin reductase, and NADPH as a reducing system. Mammalian Prxs are 20 - 30 kilodalton in molecular size and vary in subcellular localization: Prx 1, 2, and 4 in cytosol, Prx 3 in mitochondria, Prx 4 in ER and secretion, Prx 5 showing complicated distribution including peroxisome, mitochondria and cytosol (1).
Product References
1) Wood, Z. A. et al. (2003) Trends Biochem Sci. 28(1):32-40. (General)
產(chǎn)品貨號:3820.0