Adipogen/PLGF (human) (rec.)/AG-40T-0047-C005/5 ?g
重組蛋白
商品編號
AG-40T-0047-C005
品牌
Adipogen
公司
Adipogen
公司分類(lèi)
Proteins
Size
5 ?g
商品信息
More Information
Product Details
Synonyms
Placenta Growth Factor; PLGF-1; PLGF-131
Product Type
Protein
Properties
Source/Host
Sf9 cells
Sequence
Human PLGF (131aa).
Crossreactivity
Human
BIOLOG
ical Activity
Measured by its
ABI
lity to bind to immobilized rhsFlt-1 in a functional
ELISA
. Recombinant human PLGF can bind to immobilized rhsFlt-1 (100ng/well) with a linear range at 0.5-10ng/ml.
MW
~34kDa (dimer)
Purity
≥95% (SDS-PAGE)
Reconstitution
Reconstitute with 50mM acetic acid or PBS/water. This solution can be diluted into other buffered solutions or stored frozen for future use.
Formulation
Lyophilized.
Other Product Data
UniProt link P49763: PLGF (human)
Shipping and Handling
Shipping
BLUE ICE
Short Term Storage
+4°C
Long Term Storage
-20°C
Handling Advice
After reconstitution, prepare aliquots and store at -20°C.
Avoid freeze/thaw cycles.
Use/St
ABI
lity
Stable for at least 6 months after receipt when stored at -20°C.
Documents
MSD
S
Download PDF
Product Specification Sheet
Datasheet
Download PDF
Human placenta growth factor-1 (PLGF-1; PLGF) binds to the receptor FLT1/VEGFR-1. It acts as a potent chemoattractant for monocytes and only as a very weak mitogen for some endothelial cell types. The physiological function
in vivo
is still controversial. In several reports it was shown not to be a potent mitogen for endothelial cells and not angiogenic
in vivo
by using different assays. It was shown that PLGF from cell culture supernatants was angiogenic in the CAM assay and in the rabbit cornea assay.
Product References
Autocrine activity of soluble Flt-1 controls endothelial cell function and angiogenesis: S. Ahmad, et al.; Vasc. Cell
3
, 2011
產(chǎn)品貨號:3148.0