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商品編號


AG-40T-0046-C020



品牌


Adipogen



公司


Adipogen



公司分類(lèi)


Proteins



Size

20 ?g


商品信息


More Information



Product Details



Synonyms

Vascular Endothelial Growth Factor C; VRP; Flt4-L



Product Type

Protein



Properties



Source/Host

Sf9 cells



Sequence

Human VEGF-C (115aa) is fused at the C-terminus to a His-tag.



Crossreactivity

Human



MW

~18-24kDa



Purity

≥90% (SDS-PAGE)



Reconstitution

Soluble in water and most aqueous buffers. Reconstitute in PBS or medium to a concentration not lower than 50μg/ml.



Formulation

Lyophilized.



Other Product Data

UniProt link P49767: VEGF-C (human)



Shipping and Handling



Shipping

BLUE ICE



Short Term Storage

+4°C



Long Term Storage

-20°C



Handling Advice

After reconstitution, prepare aliquots and store at -20°C.
Avoid freeze/thaw cycles.



Use/St
ABI
lity

Stable for at least 6 months after receipt when stored at -20°C.



Documents



MSD
S


Download PDF



Product Specification Sheet



Datasheet


Download PDF





VEGF-C forms primarily non-covalently linked dimers. In adults, VEGF-C is highly expressed in heart, placenta, ovary and small intestine. It binds and activates VEGFR-2 (KDR/FLK1) and VEGFR-3 (FLT4) receptors. It is a growth factor active in angiogenesis and endothelial cell growth, stimulating their proliferation and migration and also has effects on the perme
ABI
lity of blood vessels. It is involved in the regulation of the growth and/or differentiation of lymphatic endothelium. It is also a mitogen for vascular endothelial cells.


Product References

Ephrin-B2 controls VEGF-induced angiogenesis and lymphangiogenesis: Y. Wang, et al.; Nature
465
, 483 (2010)

Evidence for the interaction of fibroblast growth factor-2 with the lymphatic endothelial cell
Marker
LYVE-1: N. Platonova, et al.; Blood
121
, 1229 (2013)