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商品編號


AG-40A-0142-C010



品牌


Adipogen



公司


Adipogen



公司分類(lèi)


Proteins



Size

10 ?g


商品信息


More Information



Product Details



Synonyms

Complement C1q Tumor Necrosis Factor-related Protein 5; C1QTNF5



Product Type

Protein



Properties



Source/Host

E. coli



Sequence

Human
Ctrp
5 (aa 16-243) is fused at the N-terminus to a His-tag.



Crossreactivity

Human



MW

~26kDa (SDS-PAGE)



Purity

≥90% (SDS-PAGE)



Endotoxin Content

<1eu mu;g="" purified="" protein="" (lal="" test;="" lonza).="">1eu>



Reconstitution

Reconstitute in distilled water.



Formulation

Lyophilized from a 0.2μm-filtered solution in 55mM TRIS-Cl, pH 8.2, containing 150mM NaCl.



Other Product Data

UniProt link Q9BXJ0: Complement C1q tumor necrosis factor-related protein 5 (human)



Shipping and Handling



Shipping

BLUE ICE



Short Term Storage

+4°C



Long Term Storage

-20°C



Handling Advice

After reconstitution, prepare aliquots and store at -20°C.
Avoid freeze/thaw cycles.



Use/St
ABI
lity

Working aliquots are stable for up to 3 months when stored at -20°C.



Documents



MSD
S


Download PDF



Product Specification Sheet



Datasheet


Download PDF





Ctrp
5 (C1qTNF-related protein 5; C1QTNF5) belongs to a highly conserved family of
ADI
ponectin paralogs.
Ctrp
5 mediates activation of AMP-activated protein kinase (AMPK) in muscle and liver cells, thereby regulating glucose and lipid metabolism. Serum levels of
Ctrp
5 are significantly higher in obese/diabetic animal models compared to normal controls. Fur
Thermo
re,
Ctrp
5 may be a putative bio
Marker
for mitochondrial dysfunction. Defects in C1QTNF5 are a cause of late-onset retinal degeneration (LORD).