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商品編號


EXOAB-KIT-1



品牌


SBI



公司


System Biosciences（SBI）



公司分類(lèi)


exosome detection


商品信息

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Overview:
Confirm exosome isolation with confidence

When you’re ready to confirm that you’ve isolated exosomes, stick with the exosome experts at
SBI
. Our ExoAb Antibody Kit includes antibodies to four of the most commonly used exosome
Marker
s—CD9, CD63, CD81, and HPS70. These are all polyclonal rabbit antibodies that recognize the human, mouse, and rat forms of the protein, and are a great choice for general exosome detection (if you have any questions about the best antibodies to use for your exosome project, we’re ready to help! Just email us at tech@systembio.com). And, like all of our antibodies, the antibodies in this kit, including the goat anti-rabbit HRP secondary antibodies, are rigorously validated for exosome detection via Western blotting.



Rigorously validated

Hand-picked selection

Expert exosome support


Choose the right antibody for your exosome detection needs




Cat.#

Antibody to

Notes

Link to ExoCarta entry for the human protein





General exosome
Marker
s



EXOAB-CD9A-1

CD9

Tetraspanin

ExoCarta_928



EXOAB-CD63A-1

CD63

Tetraspanin

ExoCarta_967



EXOAB-CD81A-1

CD81

Tetraspanin

ExoCarta_93185



EXOAB-Hsp70A-1

HSP70


ExoCarta_3303, ExoCarta_3304, ExoCarta_3306, ExoCarta_3308, ExoCarta 3310, ExoCarta_3311



EXOAB-ALIX-1

ALIX

Programmed cell death 6 interacting protein (PDCD6IP)

ExoCarta_10015



EXOAB-ANXA5-1

ANXA5-1

Annexin A5

ExoCarta_308



EXOAB-TSG101-1

TSG101

Tumor susceptibility gene 101

ExoCarta_7251



EXOAB-FLOT1-1

FLOT-1

Flotillin-1

ExoCarta_10211



Tissue-specific exosome
Marker
s



EXOAB-CXCR4-1

CXCR4

Specific for B-cells, T-cells, and platelets

ExoCarta_7852



EXOAB-EPCAM1-1

EpCam

Specific for cancer-derived exosomes

ExoCarta_4072



EXOAB-VMTN-1

Vimentin

Specific for mesenchymal stem cells

ExoCarta_7431





Citations:
Hsu, YL, et al. (2017) Hypoxic lung cancer-secreted exosomal miR-23a increased angiogenesis and vascular perme
ABI
lity by targeting prolyl hydroxylase and tight junction protein ZO-1.
Oncogene
. 2017 Apr 24;. PM ID: 28436951
Hao, YX, et al. (2017) KRAS and BRAF mutations in serum exosomes from patients with colorectal cancer in a Chinese population.
Oncol Lett
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Joy, M, et al. (2017) The Myocardin-related transcription factor MKL co-regulates the cellular levels of two profilin isoforms.
J. Biol. Chem.
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Medical Journal of Chinese People's Liberation Army
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Immunity
. 2017 Jun 22;. PM ID: 28666573
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Oncotarget
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Koh, YQ, et al. (2016) Characterization of exosomal release in bovine endometrial intercaruncular stromal cells.
Reprod. Biol. Endocrinol.
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McNicholas, K, et al. (2016) Albuminuria is not associated with elevated urinary vesicle concentration but can confound nanoparticle tracking analysis.
Nephrology (Carlton)
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Fischer, S, et al. (2016) Indication of Horizontal DNA Gene Transfer by Extracellular Vesicles.
PLoS ONE
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ADI
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Leukemia
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Spencer, B, et al. (2016) α-Synuclein interferes with the ESCRT-III complex contributing to the pathogenesis of Lewy body disease.
Hum. Mol. Genet.
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Silvers, CR, et al. (2016) Identification of extracellular vesicle-borne periostin as a feature of muscle-invasive bladder cancer.
Oncotarget
. 2016 Apr 26; 7(17):23335-45. PM ID: 26981774
Kouwaki, T, et al. (2016) Extracellular Vesicles Including Exosomes Regulate Innate Immune Responses to Hepatitis B Virus Infection.
Front Immunol
. 2016 Sep 16; 7:335. PM ID: 27630638
Diaz-Hidalgo, L, et al. (2016) Transglutaminase type 2-dependent selective recruitment of proteins into exosomes under stressful cellular conditions.
Biochim. Biophys. Acta
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Endo-Munoz, L, et al. (2015) Progression of Osteosarcoma from a Non-Metastatic to a Metastatic Phenotype Is Causally Associated with Activation of an Autocrine and Paracrine uPA Axis.
PLoS ONE
. 2015 Aug 31; 10(8):e0133592. PM ID: 26317203
Lee, JC, et al. (2015) Papillary thyroid cancer-derived exosomes contain miRNA-146b and miRNA-222.
J. Surg. Res.
. 2015 Jun 1; 196(1):39-48. PM ID: 25819770
Luo, X, et al. (2015) Exosomes are unlikely involved in intercellular Nef transfer.
PLoS ONE
. 2015 Apr 29; 10(4):e0124436. PM ID: 25919665
Kanada, M, et al. (2015) Differential fates of biomolecules delivered to target cells via extracellular vesicles.
Proc. Natl. Acad. Sci. U.S.A.
. 2015 Mar 24; 112(12):E1433-42. PM ID: 25713383
Amorim, M, et al. (2014) The overexpression of a single oncogene (ERBB2/HER2) alters the proteomic landscape of extracellular vesicles.
Proteomics
. 2014 Jun 1; 14(12):1472-9. PM ID: 24733759